Frequently Asked Question

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1-phenyl-2-nitropropenes to Oxime? Use Chemicals: Hydroxylamin. Oxime to Amine? Use Chemicals: NH4Cl and Zinc

Accepted Answer

The conversion of 1-Phenyl-2-Nitropropenes to an oxime can be achieved using hydroxylamine (NH2OH) in a basic environment. The nitro group is reduced to an amine, and the double bond undergoes nucleophilic attack by hydroxylamine to form the oxime. The reaction of an oxime to an amine with NH4Cl and zinc is known as a reductive amination. The zinc acts as a reducing agent, while NH4Cl provides an acidic environment. This reaction would result in the formation of a primary amine.


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