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The reaction of 2-bromobutane with hydroxide ion (OH-) is a nucleophilic substitution reaction, specifically an SN2 reaction. The hydroxide ion acts as a nucleophile, attacking the carbon atom bonded to the bromine, leading to the formation of 2-butanol and bromide ion. The reaction mechanism involves a one-step process where the nucleophile attacks the electrophilic carbon at the same time as the leaving group (bromine) departs.