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Addition of amine to a carboxylic gr
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The addition of an amine to a carboxylic acid results in the formation of an amide. This reaction, known as amidation, is a fundamental transformation in organic chemistry. The process involves the nucleophilic attack of the amine nitrogen on the carbonyl carbon of the carboxylic acid, followed by loss of water. This reaction is often catalyzed by acids or bases to enhance the reactivity of the reactants.
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