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Approximately 2-6% of ingested cadmium is actually absorbed by the human body. Once incorporated in the body cadmium concentrated mostly in the liver and kidneys and has a whole body half life of about 21 years. a. How much cadmium must be absorbed daily to maintain a 700ppb level in an 80kg person?
Accepted Answer
To determine the daily cadmium intake required to maintain a 700 ppb level in an 80 kg person, we need to consider the following:
1. Cadmium Concentration: 700 ppb (parts per billion) means 700 grams of cadmium per 1 billion grams of body mass.
2. Body Mass: The person weighs 80 kg, which is equivalent to 80,000 grams.
3. Absorption Rate: Only 2-6% of ingested cadmium is absorbed. We'll assume an average of 4% for this calculation.
4. Half-Life: The half-life of 21 years is relevant for determining the long-term accumulation but not for the daily intake calculation.
Calculation:
Cadmium Mass in Body: (700 g Cd / 1,000,000,000 g body)
80,000 g body = 0.056 g Cd
Daily Cadmium Intake: 0.056 g Cd / (0.04 absorption rate
365 days) = 0.038 g Cd/day
Therefore, approximately 0.038 grams of cadmium would need to be absorbed daily to maintain a 700 ppb level in an 80 kg person, assuming a 4% absorption rate.
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