Frequently Asked Question

Questions asked by users might not always be phrased in the clearest way.

At ph 7, which of the following amino acids has a net negative charge?rna) Cysteine.rnb) Glutamate.rnc) Arginine.rnd) Tryptophan.

Accepted Answer

At pH 7, glutamate has a net negative charge. This is because the pH of 7 is higher than the pKa of the carboxylic acid group of glutamate (about 4.3), so the carboxylic acid group is deprotonated and has a negative charge. The amino group of glutamate is protonated at pH 7 (pKa of about 9.5), so it has a positive charge. The net charge of glutamate at pH 7 is therefore -1.


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