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Both propylene glycol and glycerol are used as humectants and plasticizers, but their properties differ slightly. Propylene glycol is more volatile and can make products feel lighter, while glycerol is more viscous and can provide a more moisturizing feel. The best choice depends on the specific application and desired properties. It's worth noting that propylene glycol can be irritating to some individuals, so it's important to consider potential sensitivities.