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The CAC, or the Krebs, or Citric Acid Cycle, is a series of enzyme-catalyzed chemical reactions that occur in the mitochondrial matrix of eukaryotic cells. The CAC is used to generate ATP from glucose, and is a part of cellular respiration. The cycle begins with the condensation of acetyl-CoA and oxaloacetate to form citrate, which is then converted into isocitrate, α-ketoglutarate, succinyl-CoA, succinate, fumarate, malate, and back to oxaloacetate. During this process, electrons are transferred to NADH and FADH2, which are used to generate ATP through the electron transport chain. The CAC also produces GTP, which is used in several cellular processes.