Frequently Asked Question

Questions asked by users might not always be phrased in the clearest way.

Does PKa value depends on inductive effect

Accepted Answer

Yes, pKa value depends on the inductive effect. Inductive effect is the polarizing effect of a substituent on a carbon chain. Inductive effect is the ability of a substituent to attract or release electrons. Electron-withdrawing groups decrease the electron density of the carbon chain, making the carbon more positive and thus more acidic. Electron-donating groups increase the electron density of the carbon chain, making the carbon more basic. The pH at which half of the acid is dissociated in water is called pKa. The pKa value of an acid is a measure of its strength. Acids with lower pKa values are stronger acids than those with higher pKa values.


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