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The addition of ammonia derivatives to carbonyl compounds is an important reaction in organic chemistry, and it is essential to maintain the right acidity of the reaction medium. This is because the acidity of the medium will affect the rate of the reaction and the yield of the desired product. In general, the reaction will proceed faster in an acidic medium, but the yield of the desired product will be lower. Conversely, the reaction will proceed slower in a basic medium, but the yield of the desired product will be higher. Therefore, it is important to find a balance between the rate of the reaction and the yield of the desired product, and this can be done by adjusting the acidity of the reaction medium.