Top topic this week
Questions asked by users might not always be phrased in the clearest way.
The most common and efficient way to synthesize amides is through the reaction of a carboxylic acid with an amine. This reaction is typically catalyzed by a carbodiimide or acylation reagent. Other methods include the reaction of an acid chloride with an amine, or the reaction of an ester with an amine in the presence of a base.