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If acetophenone is reacted with 4 2 nitrobutyl morpholine and base , What exact compound would form
Accepted Answer
The reaction of acetophenone with 4-(2-nitrobutyl)morpholine in the presence of a base is a classic example of an enamine formation. The base will deprotonate the alpha-hydrogen of acetophenone, forming an enolate ion. This enolate will then react with the 4-(2-nitrobutyl)morpholine, resulting in the formation of an enamine. The exact structure of the enamine will depend on the specific base used and the reaction conditions. For example, if a strong base like sodium hydride is used, the reaction will likely proceed through a kinetic pathway, leading to the formation of the thermodynamically less stable enamine. On the other hand, if a weaker base like potassium carbonate is used, the reaction will likely proceed through a thermodynamic pathway, leading to the formation of the thermodynamically more stable enamine.
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