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Importance of Pentose phosphate pathway

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Importance of the Pentose Phosphate Pathway

- The pentose phosphate pathway generates ribose-5-phosphate, a precursor for the synthesis of nucleotides and nucleic acids.

- It provides NADPH, a reducing agent essential for reactions such as lipid synthesis and the detoxification of reactive oxygen species.

- It generates erythrose-4-phosphate, a precursor for the synthesis of aromatic amino acids and other cellular components.

- Regulates cell growth and proliferation by controlling the availability of nucleotides and NADPH.

- Plays a role in protecting cells from oxidative stress by providing NADPH for the reduction of glutathione and other antioxidants.

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