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Stereochemical relationship between endo adduct and exo adduct
Accepted Answer
The endo and exo adducts are stereoisomers formed in Diels-Alder reactions. The difference lies in the relative orientation of the substituents on the newly formed six-membered ring. In endo adducts, the substituents on the diene and dienophile are on the same side of the ring, while in exo adducts, they are on opposite sides. This distinction is driven by secondary orbital interactions during the reaction, where the endo product is favored due to the greater overlap between the π-systems of the diene and dienophile.
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