Top topic this week
Questions asked by users might not always be phrased in the clearest way.
Derivatization in gas chromatography (GC) is a process of chemically modifying a compound or analyte to make it more suitable for analysis by GC. This is done to enhance the analyte's volatility, thermal stability, or chromatographic properties, such as polarity or detectability. Derivatization can involve a variety of chemical reactions, including alkylation, acylation, silylation, and methylation. The choice of derivatization method depends on the specific analyte and the desired analytical objectives.