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Which Lewis acid is more suitable for synthesizing iminodisuccinic acid from ammonium bicarbonate and fumaric acid: zncl2 or alcl3 or cucl?
Accepted Answer
ZnCl2 is generally considered a more suitable Lewis acid for synthesizing iminodisuccinic acid from ammonium bicarbonate and fumaric acid. This is because ZnCl2 is a weaker Lewis acid than AlCl3, which can promote undesirable side reactions. CuCl, on the other hand, is less effective in catalyzing the reaction. The choice of Lewis acid can significantly impact the yield and purity of the final product.
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