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Which solvent suits maleic acid reaction with ethylenediamine: methanol or dmf?
Accepted Answer
DMF (dimethylformamide) would be a better solvent for the reaction of maleic acid with ethylenediamine. Here's why:
Polarity: DMF is a highly polar aprotic solvent, meaning it can dissolve both polar and nonpolar compounds. Maleic acid is a polar molecule, and ethylenediamine is a polar, basic compound. DMF's high polarity helps to stabilize the reaction intermediates and promote the reaction.
Hydrogen Bonding: Methanol is a protic solvent, meaning it can participate in hydrogen bonding. While this can help dissolve some reactants, it can also hinder the reaction by competing for hydrogen bonds with the reactants themselves. DMF's aprotic nature avoids this issue.
Solubility: DMF is a better solvent for both maleic acid and ethylenediamine, leading to a more homogeneous reaction mixture and better reaction kinetics.
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