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It's difficult to crown a single 'greatest' scientist in any field, as contributions are multifaceted and often build upon previous work. Chemistry has been shaped by countless brilliant minds. Some prominent figures often cited include Antoine Lavoisier for his foundational work in modern chemistry, Dmitri Mendeleev for his periodic table, Marie Curie for her pioneering work in radioactivity, and Linus Pauling for his contributions to bonding theory. Ultimately, the 'greatest' is subjective and depends on your criteria for greatness.