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Advantage and disadvantage of HPLC (short question)

Accepted Answer

Advantages of HPLC:

- High-separation efficiency
- High-speed analysis
- Can be used for both analytical and preparative separations
- Versatile and can be used for a wide range of analytes

Disadvantages of HPLC:

- Can be expensive
- Require complex and expensive instrumentation
- Method development can be time-consuming
- Can be affected by changes in temperature and pH

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