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Aldol condensation of acetone and propanal
Accepted Answer
The aldol condensation of acetone and propanal will yield two major products: 4-hydroxy-4-methylhexanal (the aldol product) and 2-methylpent-2-enal (the dehydrated product).
The reaction proceeds through the following steps:
1. Enolate formation: The enolate of acetone is formed by deprotonation with a strong base like NaOH or KOH.
2. Nucleophilic attack: The enolate of acetone attacks the carbonyl group of propanal, leading to the formation of an aldol product (4-hydroxy-4-methylhexanal).
3. Dehydration: The aldol product undergoes dehydration under acidic conditions to form an α,β-unsaturated aldehyde (2-methylpent-2-enal).
Both the aldol and dehydrated products are significant in organic synthesis.
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