Frequently Asked Question

Questions asked by users might not always be phrased in the clearest way.

Prepare a suppository containing 100mg of phenobarbital (f=0.81) using cocoa butter as the base. the weight of the pure cocoa butter suppository is 2.0g. because 100mg of phenobarbital is to be contained in an approximately 2.0g-suppository, it will be about 5% phenobarbital. what will be the total weight of each suppository? the answer should be 2.019g

Accepted Answer

The total weight of each suppository can be calculated as follows:

Weight of phenobarbital: 100 mg
Weight of pure cocoa butter suppository: 2.0 g = 2000 mg
Total weight of the suppository: Weight of phenobarbital + Weight of pure cocoa butter suppository
Total weight of the suppository: 100 mg + 2000 mg = 2100 mg or 2.1 g
Therefore, the total weight of each suppository will be 2.1 g.


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