Frequently Asked Question

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Synthesis of tetrapotassium iminodisuccinate was performed in two steps: the first step involves the addition of 8 ml of water and 4.4 g of KOH sequentially to 4.6 g of maleic anhydride, stirring for 1 hour at 50°c. the second step requires gradually heating the temperature to 110°c and stirring for 0.5 hour for the cyclization process. which ph is more suitable for the first step?

Accepted Answer

The first step in the synthesis of tetrapotassium iminodisuccinate involves the reaction of maleic anhydride with potassium hydroxide (KOH). This reaction is a basic hydrolysis, where the anhydride ring is opened by the hydroxide ions. The pH of the reaction mixture will be highly alkaline, likely around 12-14, due to the presence of a strong base (KOH). A high pH is crucial for the ring opening and formation of the potassium succinate intermediate.


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