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How is C10H15NO (phenylacetone) synthesized?
Accepted Answer
Phenylacetone (C10H15NO) can be synthesized through various methods, but a common approach involves the following steps:
1. Reaction of Phenylacetic Acid with Methylamine:
- Phenylacetic acid is reacted with methylamine in the presence of a suitable catalyst, such as a strong acid (e.g., HCl), to form phenylacetone.
2. Acylation of Phenylmethyl Ketone:
- Phenylmethyl ketone can be acylated using acetic anhydride to produce phenylacetone.
3. Catalytic Hydrogenation of Benzaldehyde:
- Benzaldehyde can be catalytically hydrogenated in the presence of a metal catalyst (e.g., palladium) to yield phenylacetone.
Note that these are just examples, and other methods may be employed depending on the specific requirements and desired purity of the final product.
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