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The equivalence point in potentiometric titration is determined by observing the inflection point on the titration curve, which is the point where the pH changes most rapidly with the addition of the titrant. To locate the equivalence point accurately, the second derivative of the titration curve can be plotted, which will show a sharp peak at the equivalence point. The equivalence point can also be determined by using a pH meter to monitor the pH of the solution during the titration. The equivalence point is the point at which the pH of the solution changes most rapidly with the addition of the titrant.