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Strong field ligands cause a large splitting of the d orbitals in a transition metal complex, leading to low-spin complexes. Weak field ligands cause a small splitting, resulting in high-spin complexes. This difference in splitting is due to the strength of the ligand field, which is determined by the ligand's ability to donate electrons to the metal ion. Strong field ligands are typically small and highly electronegative, while weak field ligands are larger and less electronegative.