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Calculate the number of appropriate tablets of Prednisone required to prepare a suspension for a child weighing 15kg to fulfil the following directions: sig.1mg/kg bid 1st day; 0.5mg/kg bid 2nd day 0.25mg/kg bid 3rd day; 0.125mg/kg bid 4th day 0.125mg/day 5th day; 0.125mg/day 6th day available strength of Prednisone tablets: 5mg and 25mg
Accepted Answer
Day 1:
Dose: 1mg/kg bid = 1mg/kg
2 = 2mg/kg
Total daily dose: 2mg/kg
15kg = 30mg
Tablets needed: 30mg / 5mg/tablet = 6 tablets (use 5mg tablets)
Day 2:
Dose: 0.5mg/kg bid = 0.5mg/kg
2 = 1mg/kg
Total daily dose: 1mg/kg
15kg = 15mg
Tablets needed: 15mg / 5mg/tablet = 3 tablets (use 5mg tablets)
Day 3:
Dose: 0.25mg/kg bid = 0.25mg/kg
2 = 0.5mg/kg
Total daily dose: 0.5mg/kg
15kg = 7.5mg
Tablets needed: 7.5mg / 5mg/tablet = 1.5 tablets (use 1 5mg tablet and 1/2 5mg tablet)
Day 4:
Dose: 0.125mg/kg bid = 0.125mg/kg
2 = 0.25mg/kg
Total daily dose: 0.25mg/kg
15kg = 3.75mg
Tablets needed: 3.75mg / 5mg/tablet = 0.75 tablets (use 1/2 5mg tablet)
Day 5 & 6:
Dose: 0.125mg/day
Total daily dose: 0.125mg/day
15kg = 1.875mg
Tablets needed: 1.875mg / 5mg/tablet = 0.375 tablets (use 1/2 5mg tablet)
Dose: 1mg/kg bid = 1mg/kg
2 = 2mg/kg
Total daily dose: 2mg/kg
15kg = 30mg
Tablets needed: 30mg / 5mg/tablet = 6 tablets (use 5mg tablets)
Day 2:
Dose: 0.5mg/kg bid = 0.5mg/kg
2 = 1mg/kg
Total daily dose: 1mg/kg
15kg = 15mg
Tablets needed: 15mg / 5mg/tablet = 3 tablets (use 5mg tablets)
Day 3:
Dose: 0.25mg/kg bid = 0.25mg/kg
2 = 0.5mg/kg
Total daily dose: 0.5mg/kg
15kg = 7.5mg
Tablets needed: 7.5mg / 5mg/tablet = 1.5 tablets (use 1 5mg tablet and 1/2 5mg tablet)
Day 4:
Dose: 0.125mg/kg bid = 0.125mg/kg
2 = 0.25mg/kg
Total daily dose: 0.25mg/kg
15kg = 3.75mg
Tablets needed: 3.75mg / 5mg/tablet = 0.75 tablets (use 1/2 5mg tablet)
Day 5 & 6:
Dose: 0.125mg/day
Total daily dose: 0.125mg/day
15kg = 1.875mg
Tablets needed: 1.875mg / 5mg/tablet = 0.375 tablets (use 1/2 5mg tablet)
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